Transforaminal Lumbar Interbody Fusion (TLIF) in San Diego, CA | Dr. Sanjay Ghosh 

Stable Relief for Lower Back Pain, Leg Pain & Spinal Instability 

Lower back pain, shooting leg pain, and spinal instability can make simple tasks feel impossible. When nerves remain compressed and the lower spine becomes unstable, Transforaminal Lumbar Interbody Fusion (TLIF) offers a safe and effective path back to strength, stability, and comfort. 

Dr. Sanjay Ghosh, a board-certified neurosurgeon in San Diego, specializes in minimally invasive TLIF techniques designed to decompress nerves, restore spinal alignment, and prevent recurring pain. 

Call (619) 810-1010 to schedule your lumbar spine consultation. 

What Is TLIF? 

Transforaminal Lumbar Interbody Fusion (TLIF) is a surgical procedure that stabilizes the lower spine by removing a damaged lumbar disc and fusing two vertebrae together. 

Unlike other fusion techniques, TLIF uses a posterior, muscle-preserving approach through one side of the spine. This allows Dr. Ghosh to decompress irritated nerves, rebuild disc height, and restore stability in a controlled, minimally invasive manner. 

The result: reduced nerve irritation, improved alignment, and long-lasting support for your lower back. 

Conditions TLIF Treats 

TLIF is most often recommended for: 

  • Lumbar degenerative disc disease 
  • Spondylolisthesis (slipped vertebra) 
  • Recurrent disc herniation 
  • Spinal instability or vertebral collapse 
  • Severe lumbar stenosis with instability 
  • Nerve compression causing leg pain or weakness 
  • Failed prior lumbar surgery requiring stabilization 

If you have chronic lower back or leg pain that limits walking, bending, or standing, TLIF may be an effective option. 

Common Symptoms Before TLIF 

Patients who benefit from TLIF often experience: 

  • Persistent lower back pain 
  • Shooting leg pain (sciatica) 
  • Numbness or tingling down the leg 
  • Weakness in the feet or legs 
  • Pain when bending, lifting, or twisting 
  • Trouble standing or walking long distances 
  • Instability or “slipping” sensations in the lower spine 

A clear diagnosis helps guide the right treatment plan. 

How TLIF Is Performed 

Dr. Ghosh uses a minimally invasive approach whenever appropriate. 

General steps include: 

  1. A small incision is made on one side of the lower back 
  1. Muscles are gently separated, not cut 
  1. Damaged disc and bone are removed to decompress the nerve 
  1. A disc spacer or cage is placed between vertebrae 
  1. Bone graft is added to promote fusion 
  1. Screws and rods are placed for stability 
  1. The spine gradually fuses over the coming months 

The goal is to relieve nerve pressure, stabilize the spine, and prevent future slippage or disc collapse. 

Benefits of TLIF 

Patients often choose TLIF because it offers: 

  • Reliable relief from lower back and leg pain 
  • Improved stability for walking, standing, and daily activity 
  • Restoration of disc height, reducing nerve compression 
  • Minimally invasive options for less muscle disruption 
  • Improved alignment of lumbar vertebrae 
  • Reduced risk of recurrent disc herniation 
  • More natural biomechanics than some other fusion approaches 

TLIF remains one of the most effective and durable fusion techniques for the lumbar spine. 

Why Patients Choose Dr. Ghosh for TLIF 

  • Board-certified neurosurgeon 
  • 20+ years of lumbar spine surgical experience 
  • Fellowship-trained in complex and minimally invasive spine surgery 
  • Skilled in both primary and revision TLIF procedures 
  • Focus on restoring movement and long-term spinal stability 
  • Uses advanced imaging and navigation for accurate hardware placement 
  • Performs surgery at Scripps Memorial Hospital La Jolla and accredited outpatient centers 

Dr. Ghosh is known for giving patients clear explanations, conservative-first recommendations, and precise surgical care. 

What to Expect Before, During & After Surgery 

Before TLIF 

  • Thorough review of MRI/CT scans 
  • Evaluation of symptoms, mobility, and nerve function 
  • Discussion of non-surgical options attempted 
  • Personalized treatment plan 

During Surgery 

  • Small minimally invasive incision 
  • Safe decompression of nerves 
  • Placement of interbody spacer + bone graft 
  • Stabilization with screws and rods 

After Surgery 

  • Walking encouraged the same day 
  • Light activity is typically allowed within a week 
  • Gradual strengthening and endurance over time 
  • Fusion matures over several months 
  • Physical therapy may support recovery 

Patients often feel leg pain improve first, followed by gradual relief of lower back pain as healing continues. 

Non-Surgical Alternatives to TLIF 

Not every patient needs lumbar fusion. Dr. Ghosh may recommend: 

  • Physical therapy 
  • Image-guided lumbar injections 
  • Stabilization exercises 
  • Activity modification 
  • Medications 
  • Microdiscectomy (if the disc is herniated but the spine is stable) 

TLIF is considered only when symptoms persist and instability is confirmed. 

Frequently Asked Questions

Is TLIF a minimally invasive procedure?

Yes. Dr. Ghosh uses muscle-sparing techniques and small incisions whenever possible. 

Many patients return to light work within a few weeks, depending on job type. 

Yes. By decompressing the nerve and restoring disc height, TLIF often improves leg pain. 

Yes. Fusion stabilizes the slipped vertebra and prevents further movement. 

Bone fusion develops over several months and continues strengthening over time. 

TLIF enters through one side of the spine, reducing nerve manipulation and lowering complication risk. 

Serving Patients Across San Diego County 

Dr. Ghosh cares for patients from Carlsbad, La Jolla, Encinitas, Mission Valley, Poway, Rancho Bernardo, Mira Mesa, Hillcrest / Bankers Hill, Clairemont, Chula Vista, Coronado, Del Mar, Scripps Ranch, University City / UTC, and nearby communities throughout San Diego County. His Mission Valley clinic is convenient and easy to reach. 

Related Conditions Dr. Ghosh Treats 

Many patients who need TLIF also struggle with other lumbar spine conditions. Dr. Ghosh provides expert diagnosis and treatment for: 

Lumbar Spinal Stenosis 

Narrowing of the spinal canal can cause back pain, leg pain, or difficulty walking. 

Lumbar Radiculopathy (Pinched Nerve) 

Nerve irritation from disc collapse, bone spurs, or instability that leads to leg pain, numbness, or weakness. 

Herniated Disc (Lower Back) 

A damaged lumbar disc pressing on nearby nerves, often causing sharp, shooting pain down the leg. 

Spondylolisthesis 

A slipped vertebra that creates instability in the lower spine and may require fusion to prevent worsening symptoms. 

Degenerative Disc Disease 

Age-related disc wear that leads to chronic back pain, reduced mobility, and occasional nerve irritation. 

Find Relief from Lower Back and Leg Pain 

If lower back pain, sciatica, or instability is affecting your life, TLIF may offer a long-term solution. Dr. Sanjay Ghosh provides advanced lumbar fusion techniques designed to restore stability and relieve nerve pressure. 

Call (619) 810-1010 or request your consultation online to see if TLIF is right for you. 

Real Lives Transformed

Patients who regained strength and independence through precise, compassionate care.

Schedule a Consultation

If you’ve been diagnosed with an acoustic neuroma or are experiencing symptoms such as hearing loss or dizziness, contact Dr. Ghosh to discuss the best treatment options for you. Our team provides compassionate, evidence-based care tailored to each patient’s unique condition and lifestyle.

Meet Elisha
Elisha G.
Practice Relations Liaison

Proudly partnering with Elisha Green – Practice Relations Liaison.

Meet Lauren
Lauren G.
Assistant Office Manager

Lauren was born and raised in San Diego, California. She attended San Diego State University, graduating with a Bachelor of Arts degree in Communication in 2013. She began her professional journey in the hospitality field where she discovered her passion for helping others and building relationships. This eventually inspired her to pursue a career in healthcare, joining Sharp Healthcare in 2016 where she found great fulfillment in learning and growing within the medical field. Lauren began working with Senta Neurosurgery in 2017 supporting Dr. Sanjay Ghosh.

When not at work, Lauren enjoys spending time with her family, being an Auntie, traveling, and being outdoors.

Dr. Ghosh, I just wanted to take a moment & thank you again for all you have done for my husband, Benton (Rick) Coulter. June 26th he was brought by ambulance to Grossmont Hospital. That was the beginning of the scariest days of our lives. When we were told he needed brain surgery we were stunned, confused & not sure what to do. We asked for a second opinion by you. Within 30 minutes you were at Rick’s bedside. You were friendly, caring & confident. After examining him you told us he would need two surgeries instead of one. You even called me at home to answer our many questions. Thank you for treating us with such respect. You were available & patient as we tried to make a decision. Once we decided you were the right Dr. we had continuous confirmations that we had chosen the right one. We will be forever grateful to you! You saved my husband’s life and his sight. God used you in a mighty way & He answered our prayers. Thank you for all the work it took to be a Brain Surgeon & to help others like us. You are not only skilled but you are also caring. We appreciate you so much.
Sincerely, Karen Coulter
So far I have been taken great care of by Dr. Ghosh and his staff. Dr. G has spent quality time with me reviewing my symptoms and MRI’s etc that are a result of a day at a water park turn into one of the worst injuries I have ever had. What I appreciated the most was our efforts as a team to exhaust all options of pain management and PT before coming to the decision that no relief is in sight without surgery. I had already been referred to Dr. G’s office by other friends and patients so I’m very comfortable moving forward with Dr. Ghosh and his team.
Former Patient
I was referred to Dr. Ghosh by my corporate physician. She had heard good things about Dr. Ghosh. I went to several other neurosurgeons. They were all excellent but I just liked Dr. Ghosh’s confidence and frank manner. My surgery was quick and the result was excellent. My recovery time was minimal. The incision, with a little more time will be minimal and not noticeable. The pain I have felt for a long time is gone. I’ve noticed that others feel that Dr. Ghosh and Amanda did not spend enough quality time with them. My time with them was brief. I don’t need alot of hugs and hand holding. I just needed them to provide me with the information I needed to make decisions, which they did to my satisfaction. They are seeing alot of patients. I don’t think it would be fair to others if Dr. Ghosh and Amanda had to spend several hours caring for my psychological needs when all they really needed to do is fix my neck. Amanda is truly capable. I had an issue late on a holiday night. I called. They transferred me to her even though she was at a social event. I explained to her my concerns. She told me what to expect and under what circumstances to come back to the office.For those who felt abandoned and that they didn’t get enough time, you might find other surgeons even more unavailable. Dr. Ghosh stated he was starting to take less patients to try and spend a little more time with each patient. I hope he doesn’t. It won’t be fair to the people who won’t benefit from his talents. A special thank you to Dr. Ghosh and his team.
Former Patient
Meet Edith
Edith Smith
Director of Operations

Edith was born in Budapest, Hungary and immigrated to Los Angeles, CA as a small child.  She later received a Bachelor of Arts degree in Economics from the University of California, San Diego in 1996. From 1997 to 2002, she worked as a Program Manager at Qualcomm, during which time she also obtained a Certificate in Project Management from the University of San Diego. Edith took some time off to start her family but remained active in her volunteer efforts supporting Rady Children’s Hospital Auxiliary, where she co-chaired nine large fundraising events and served on the Board of Directors for 5 years. During her time at Rady Children’s, Edith became passionate about healthcare and neurosurgery in particular when her daughter became a neurosurgical patient at Radys. Edith joined Senta Neurosurgery’s team supporting Dr. Sanjay Ghosh’s practice in 2019. Given her personal experiences, Edith knows that getting a referral to neurosurgery is a stressful, life altering event, so she truly appreciates being part of the patient care process for Dr. Ghosh’s patients.

When not at work, Edith enjoys spending time with her friends and family, traveling, cooking, and entertaining.

Meet Melissa
Melissa Padilla
Surgery Coordinator

Melissa has an Associate of Science Degree in Medical Office Administration. She has worked in healthcare for over 25 years. She started out working in a radiology department processing film and scheduling exams. Melissa joined Dr. Ghosh’s team in 2003 and uses her skills and experience to schedule Dr. Ghosh’s patients for surgery.  She is a fierce advocate for our patients throughout the entire prior authorization and scheduling process, and her goal is to make the scheduling of our patients’ surgeries organized and stress free so that our patients can focus on healing.

Meet Deborah
Deborah Updike
M.M.S, M.S., PA-C

Deborah is a California native. She attended American University in Washington, DC graduating with a Bachelor of Science in Marine Science and Environmental Studies. She was a college athlete, playing NCAA D1 volleyball all four years. She then attended California State University, Long Beach where she received a Masters of Marine Science in Shark Reproductive Physiology. During her first masters degree, she began transitioning into medicine and went on to receive her Master of Medical Science degree in Physician Assistant studies at Midwestern University in Downers Grove, IL. Deborah served as class Vice President. She graduated in 2017 and has been working at Senta Neurosurgery ever since. Deborah is a member of the American Academy of Physician Assistants.

Meet Edith
Edith Smith
Director of Operations

Edith was born in Budapest, Hungary and immigrated to Los Angeles, CA as a small child.  She later received a Bachelor of Arts degree in Economics from the University of California, San Diego in 1996. From 1997 to 2002, she worked as a Program Manager at Qualcomm, during which time she also obtained a Certificate in Project Management from the University of San Diego. Edith took some time off to start her family but remained active in her volunteer efforts supporting Rady Children’s Hospital Auxiliary, where she co-chaired nine large fundraising events and served on the Board of Directors for 5 years. During her time at Rady Children’s, Edith became passionate about healthcare and neurosurgery in particular when her daughter became a neurosurgical patient at Radys. Edith joined Senta Neurosurgery’s team supporting Dr. Sanjay Ghosh’s practice in 2019. Given her personal experiences, Edith knows that getting a referral to neurosurgery is a stressful, life altering event, so she truly appreciates being part of the patient care process for Dr. Ghosh’s patients.

When not at work, Edith enjoys spending time with her friends and family, traveling, cooking, and entertaining.

Meet Felix
Felix Regala
MPAP, PA-C

Felix was born and raised in Abilene, Texas where he graduated from Abilene High School in 2001. He was honored with the Chuck and Doris Moser Scholarship for his accomplishments as a varsity athlete in baseball and his excellence in academics and community service. He then attended Baylor University where he graduated in 2004 with a Bachelor of Science degree in biology. Felix then spent a couple of years working in the laboratory at the Salk Institute for Biological Studies and Johnson & Johnson. He then went on to the Keck School of Medicine at University of Southern California to obtain his Master of Physician Assistant Practice degree. Felix graduated from physician assistant school in 2010. While pursuing his PA degree at USC, Felix served as class president and spent time training in neurosurgery and orthopedic spine.  Felix has been a PA with Dr. Ghosh since May 2011.

Felix enjoys being active, including playing basketball, surfing, snowboarding, golfing, and exercising. Felix is also a member of the American Academy of Physician Assistants and the California Academy of Physician Assistants.

Meet Amanda
Amanda W. Gumbert
M.M.S, PA-C

Amanda received her Bachelor of Science degree in Kinesiology at San Diego State University in 2002. She worked as an Exercise Physiologist at the Cardiac Treatment Center at Scripps Memorial Hospital La Jolla before going to PA School. Amanda graduated from Midwestern University in Glendale, Arizona with a Master of Medical Science degree in Physician Assistant studies in 2005. She began working for Dr. Ghosh in January 2006 working as the senior Physician Assistant and manager of the PAs.   Amanda has spoken at the national level at the AAPA conference on various neurosurgical topics. She is highly committed to the future Physician Assistants and frequently has students shadow her and acts as a PA student preceptor. She is a member of the American Academy of Physician Assistants, Association of Neurosurgical Physician Assistants, and The San Diego Society of Physician Assistants.  Amanda is honored to be a finalist for San Diego Magazine’s Woman of the Year— 2025 Healthcare Pioneer.

When not working, Amanda enjoys hiking, mountain biking, stand up paddle boarding, snowboarding, playing with her dogs and spending time with her family.

San Diego Magazine’s Celebrating Women
2025 Healthcare Pioneer Finalist